Ayisha Sami serves as an Advisor and Director at Sami Capital, where she combines entrepreneurial experience, strategic insight, and values-driven leadership to help physicians and business owners take control of their wealth, taxes, and long-term legacy.

A graduate of dental surgery, Ayisha transitioned from clinical healthcare into business strategy and family office operations playing a pivotal role in the creation, growth, and successful exit of Chicago Telerad, acquired by the Pritzker family–backed Epic Staffing Group. Her firsthand experience in building, scaling, and exiting a physician-led enterprise gives her a unique perspective on both the challenges and opportunities faced by entrepreneurial families.

At Sami Capital, Ayisha serves as a key strategist, guiding initiatives across family governance, organizational development, and wealth coordination. She works closely with the leadership team to ensure that every client engagement reflects the same clarity, coordination, and care that she and her family have built within their own Virtual Family Office.

As the co-architect of the Sami family’s VFO framework, Ayisha’s philosophy is simple yet profound: true wealth is about more than numbers—it’s about peace of mind, shared purpose, and passing on a legacy with intention.